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Tumor Organoid Scientist

With the advent of genomic sequencing, we can finally decode and process our genetic
makeup. We now have more data than ever before but providers don't have the
infrastructure or expertise to make sense of said data. Here at Tempus, we believe the
greatest promise for the detection and treatment of cancer lies in the deep
understanding of molecular activity for disease initiation, progression, and efficacious
treatment based on the discovery of unique biomarkers.

We're on a mission to connect an entire ecosystem to redefine how genomic data is
used in clinical settings. We're looking to build a laboratory operations team who are
passionate and focused on developing state of the art techniques to processing and
creating and interpreting vast amounts of genomic and molecular data from patients and
from biological models. While developing and screening organoid models directly from
patient tumor samples, scientists will collaborate with product, research, and business
development teams to develop the most advanced sequencing platform in cancer care.

What you will do:

  • Work with a cutting-edge biological modeling and organoid screening workflow to provide high-quality cellular analyses and drug screening data
  • Collect and analyze data to present results from tumor organoid drug screening assays
  • Interpret tumor organoid drug screening results in order to design new assays
  • Critically evaluate literature related to 3D tumor organoids to translate recent developments into laboratory use.
  • Develop high quality, robust, reproducible SOPs and documentation for all projects.
  • Maintain best practices and SOPs to ensure reproducibility and reliability of all research results.
  • Work in interdisciplinary groups of scientists, engineers and product developers to translate research from our models into actionable insights.

Must have:

  • M.S. in biological sciences with 6+ years, or PhD with 3+ years of experience in Cancer Biology or biological sciences related to cancer.
  • Demonstrated experience working with tumor organoid-based drug screening platforms
  • Deep knowledge of tumor organoid model’s biology and challenges
  • Demonstrated experience working with live-cell analysis systems
  • Ability to work with others to plan and carry out scientific programs
  • Demonstrated ability to conceive, implement and evaluate research projects for complex biological problems
  • Self-driven and works well in an interdisciplinary team with minimal direction
  • Excellent communication skills
  • Thrives in a fast-paced environment

Highly desirable:

  • Proficient in statistical data analysis
  • Experience working with next-generation sequencing data
  • Computer programming skills
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